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GWASTic Documentation
  • 👋Welcome to GWAStic documentation
  • Overview
    • 💡Video Tutorials
    • ✨Features
  • Fundamentals
    • đŸ–Ĩī¸Installing GWAStic
    • đŸ–Ĩī¸Starting GWAStic
    • â†Ēī¸Converting VCF to BED files
    • 🔄GWAS Analysis
    • 🔄Genomic Prediction
    • Running from command line
    • Algorithms
    • Effect size and P-value
    • Train, Test, and Validation Sets
    • Settings
    • â„šī¸References
    • Version history
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  • Supported file formats
  1. Fundamentals

Converting VCF to BED files

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Last updated 10 months ago

Convert

  1. Choose VCF: Click to upload a Variant Call Format (VCF) file, which contains genetic variation data.

  2. Choose variants (optional): Optionally upload a file with specific genetic variants to be included in the conversion process.

  3. MAF input box: Set the minor allele frequency (MAF) threshold for filtering variants. Variants with a MAF below this value will be excluded.

  4. Missing genotype rate input box: Enter the maximum allowable rate of missing genotypes per variant. Variants with missing data above this rate will be excluded.

  5. Convert button: Start the conversion of the VCF file to the BED/BIM/FAM file format, applying the specified MAF and missing genotype filters.

Supported file formats

VCF file format (including vcf.gz) and PLINK BED/BIM/FAM format are supported for all GWAS methods. The VCF files must converted to BED/BIM/FAM file format.

â†Ēī¸
https://github.com/snowformatics/data/blob/cd8ac371fe669711430a6a4d7c00960082b3cd4b/gwastic_test_data/example.vcf.gz
VCF example file